The Ministry of Science and ICT (MSIT), led by Vice Prime Minister and Minister Baek Kyeong-hoon, announced that the Korea Nano Technology Research Institute (Korea Nanotechnology Research Center, Director Heung-Soo Park, hereinafter “K-NTRC”) has successfully commercialized an integrated next-generation digital Polymerase Chain Reaction (digital PCR) system for cancer diagnostics through scale-up of the “microwell molded disk and its manufacturing method” and subsequent technology transfer.

A microwell refers to an array of extremely small wells, primarily used in various biotechnology research and diagnostic applications—including cell culture, drug development, and genetic analysis.

Since 2021, K-NTRC and RevoSketch Co., Ltd. have pursued commercialization of their source technologies, including digital PCR for cancer diagnostics and microwell fabrication technologies, as well as performance validation through research-based clinical studies. Through a recent technology transfer (December 2, 2025), the institutes have applied semiconductor imprinting process technology to secure high manufacturability—1 million units per year—and a production yield of 99%, laying the foundation for full-scale mass production.

Imprinting process technology is a nano-patterning method in which a mold engraved with nanoscale patterns is physically pressed onto a substrate to form nano structures.